Thrombolysis and mechanical intervention following myocardial infarction

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Thrombolysis and mechanical intervention following myocardial infarction.

In concept, mechanical interventions are attractive options for treating acute myocardial infarction with or without preceding thrombolysis: rapid reperfusion of the infarct-related artery can be achieved in the vast majority of cases, and the underlying coronary lesion is treated at the same time. Various strategies have been extensively investigated. When performed in specialized centres, dir...

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Mechanical complications following acute myocardial infarction.

OBJECTIVE To outline the outcome and management of patients with acute myocardial infarction presenting with mechanical complications such as post-infarction ventricular septal defect, mitral regurgitation and left ventricular rupture. METHODS The retrospective study, conducted in September and October, 2010 at the Aga Khan University Hospital, Karachi, included cases from January 1990 to Dec...

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Thrombolysis for Myocardial Infarction

Background. Coronary patency has been used as a measure of thrombolysis success after acute myocardial infarction. The Thrombolysis in Myocardial Infarction (TIMI) Study Group perfusion grades have gained wide acceptance, with grades 0 (no distal flow) and 1 perfusion (minimal flow) being designated as thrombolysis failures and grades 2 (partial perfusion) and 3 (complete perfusion) as thrombol...

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Acute myocardial infarction: thrombolysis.

nfarction is the most intensively studied medical intervention in the history of clinical investigation, with more than 200 000 patients enrolled in large scale, worldwide trials. The results of these trials have led to an irrevocably altered approach, with routine use of reperfusion treatment. Streptokinase, tissue plasminogen activator (t-PA), and new plas-minogen activators have been shown t...

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Thrombolysis in Myocardial Infarction

Worldwide around 7 million people suffer myocardial infarctions per year according to White et al. (2008). Around one third of these patients having acute myocardial infarction die within the first hour of having symptoms usually due to fatal arrhythmia. Characteristic ST segment elevation in the 12 lead electrocardiogram (ECG) accompanied by clinical symptoms of chest pain provide the most rap...

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ژورنال

عنوان ژورنال: European Heart Journal

سال: 1996

ISSN: 0195-668X,1522-9645

DOI: 10.1093/eurheartj/17.suppl_e.49